Endocrine Abstracts

Introduction and objectives: The aim of our study was to determine which characteristics of the uncontrolled diabetes are among randomly selected patients with type 1 (T1DM) and type 2 (T2DM) diabetes.Material and methods: A total of 194 diabetic patients were observed, 142 with T2DM and 52 with T1DM, recruted in outpatient clinic. Patients were divided into three groups according to HbA1c values: <7% (G1), 7–8% (G2) and >8% (G3). Statistica...

Introduction: Hypogonadotropic hypogonadism(HH) is mandatory treated with testosterone (T). However, gonadotropin(hCG/FSH) administration might be the challenging optimal therapy.Case 1: Male, 23-y-old, hypophisectomy pp. adenoma hromophobum, one month later- FSH 1.5 U/L, LH 0.55 U/L. Primogonyl(hCG) test; testosteronemia: 0 day 0.069, 3 day 19.01 nmol/l. After 5 m in ejaculate no sperm. 5 m after introduction of hCG twice weekly 1,500 i.u. and FSH+LH 15...

The prevalence of osteoporosis among men is not well-documented. The aim of this cross-sectional study is to analyze results of DXA scans preformed in males in Clinical center of Vojvodina between years 2009 and 2016. Form the total of 2006 fist DXA scans performed in 7 years period there was 14.8% of males. DXA scan was indicated by the rheumatologists, internists and endocrinologists predominantly for suspected secondary causes of osteoporosis. We divided male subjects in gr...

Introduction and objective: Cardiovascular mortality is high in acromegaly. Our aim in this study was to determine the levels of the new cardiovascular marker in active acromegaly patients, the mean platelet volume (MPV) values before and after octreotide acetate LAR treatment.Material and methods: Thirty-six patients with active acromegaly who presented at the endocrinology department (mean age 46.0±14.0 years and mean BMI: 30.4±5.1 kg/m2...

Primary hyperparathyroidism is an autonomous form of hyperparathyroidism, whose characteristics are: increased secretion of parathyroid hormone with clinical signs of hypercalcemic syndrome and various organ lesions, including bones.Case report: A 51-year-old Caucasian female presented with walking difficulties, polyuria, polydipsia, palpitations and headaches. Examination showed thoracic spine hyperkyphosis with consecutive chest deformity, staggered wa...

Introduction: Congentital adrenal hyperplasia (CAH) comes to adult endocrinologist wheather as transition from pediatritian (Case 3) or as still without diagnosis (Case 1, 2, 4). The aim of this work is to describe typical forms of CAH initially sucessfuly treated with dexamethasone therapy.Case descriptions: Case 1: female, 1972y., presented in 1995y. (23y.) as severe hirsutism and infertility managed by team of gynecologists. She refus...

Introduction: It is indisputable importance of vitamin D for the preserved integrity of the skeleton and bone metabolism.The aim of the study was to analyse bone turnover parameters in relation to the vitamin D status in women with postmenopausal osteoporosis.Materials and methods: This study included a total of 195 postmenopausal women with osteoporosis. Osteoporosis is diagnosed by DXA scan of the spine and hip. Bone turnover mar...

Introduction: Literature data suggests increased fracture risk in women with diabetes mellitus type 2 but the underlying mechanism is not fully understood.Aim of the study was to analyse bone turnover parameters in women with DM2 and in healthy women with osteoporosis in menopause.Materials and methods: There were 76 participants out of wich 36 women with DM2. Average diabetes duration was 14.48±10.51 years with mean HbA1c 7.8...

Introduction: MTC originates from the parafollicular calcitonin secreting cells. One quarter of MTC patients have familial form of the disease with RET mutation.Case reports: First female patient underwent total thyroidectomy for MTC at the age 40. Further investigation showed elevated urinary catecholamine levels and MIBG scintiscan verified bilateral pheochromocytoma. Bilateral adrenalectomy was performed. On follow-up basal and stimulated calcitonin l...

Introduction: Although diagnostics and therapy are much improved over the years, women with gestational diabetes still have more adverse course and outcome of pregnancy than healthy women. Their pregnancies are more often complicated with the different forms of maternal and fetal morbidity. Our study investigates all cause early neonatal morbidity (neonatal jaundice, neonatal hypoglycemia, fetal distress syndrome and other) and newborns maturity and vitality in the groups of d...